Search results for "case–control study"

showing 6 items of 6 documents

BODY MASS INDEX DOES NOT CHANGE BEFORE PARKINSON'S DISEASE ONSET.

2008

Background and purpose:  Previous studies on the association between Parkinson’s disease (PD) and body mass index (BMI) have reported conflicting results. We investigated the relationship between PD and BMI by a case–control study. Methods:  PD patients were randomly matched to healthy individuals by sex and age. BMI distribution in cases has been compared with BMI of controls and odd ratios (ORs) with 95% CI were calculated. Results:  We included 318 PD patients and 318 controls. We observed no association between PD and BMI. BMI distribution in cases and controls was similar also when we adjusted for diabetes, hypercholesterolemia and the time elapsed between PD onset and the interview (O…

AdultMalemedicine.medical_specialtyParkinson's diseaseHypercholesterolemiaPopulationComorbidityWeight GainCoffeeBody Mass IndexRisk FactorsInternal medicineDiabetes mellitusWeight LossEpidemiologyDiabetes MellitusmedicineHumansObesityAge of OnseteducationAgedAged 80 and overHypertriglyceridemiaeducation.field_of_studybusiness.industrySmokingCase-control studynutritional and metabolic diseasesParkinson DiseaseMiddle AgedOverweightmedicine.diseaseNeurologyCase-Control StudiesHealthy individualsanthropometrical measures body mass index case–control study epidemiology Parkinson's disease risk factorsPhysical therapyFemaleSettore MED/26 - NeurologiaNeurology (clinical)businessBody mass index
researchProduct

Nonparticipation Selection Bias in the MOBI-Kids Study.

2018

Supplemental Digital Content is available in the text.

GerontologyMaleAdolescentCellular telephone useEpidemiologyCase–control studymedia_common.quotation_subjectEpidemiologic methodsAdolescents01 natural sciencesBrain tumorsBrain cancer010104 statistics & probability03 medical and health sciencesYoung Adult0302 clinical medicineElectromagnetic FieldsAge groupsBiasJapanRisk FactorsGermanySurveys and QuestionnairesPerinatal and Child HealthOdds RatioHumans030212 general & internal medicine0101 mathematicsIsraelChildChildrenmedia_commonSelection biasSelection biasBrain NeoplasmsCase-control studyItalySpainCase-Control StudiesComputingMethodologies_DOCUMENTANDTEXTPROCESSINGFemaleFrancePsychologyCell PhoneEpidemiology (Cambridge, Mass.)
researchProduct

Childhood leukemia and residential proximity to industrial and urban sites

2015

BACKGROUND: Few risk factors for the childhood leukemia are well established. While a small fraction of cases of childhood leukemia might be partially attributable to some diseases or ionizing radiation exposure, the role of industrial and urban pollution also needs to be assessed. OBJECTIVES: To ascertain the possible effect of residential proximity to both industrial and urban areas on childhood leukemia, taking into account industrial groups and toxic substances released. METHODS: We conducted a population-based case-control study of childhood leukemia in Spain, covering 638 incident cases gathered from the Spanish Registry of Childhood Tumors and for those Autonomous Regions with 100% c…

MaleChildhood leukemiaAdolescentCase–control studyPopulationIndustrial pollutionChildhood leukemiaLogistic regressionUrban pollutionBiochemistryResidence CharacteristicsEnvironmental healthmedicineResidential proximityHumansRisk factoreducationChildGeneral Environmental Scienceeducation.field_of_studyLeukemiaAbsolute risk reductionUrban HealthOdds ratiomedicine.diseaseLeukemiaSpainCase-Control StudiesResidenceFemale
researchProduct

Occupational solvent exposure and risk of glioma in the INTEROCC study

2017

BACKGROUND: The aetiology of glioma remains largely unknown. Occupational solvent exposure has been suggested as a putative cause of glioma, but past studies have been inconsistent. We examined the association between a range of solvents and glioma risk within the INTEROCC project, a study of brain tumours and occupational exposures based on data from seven national case-control studies conducted in the framework of the INTERPHONE study. We also investigated associations according to tumour grade.METHODS: Data from the seven countries were standardised and then combined into one aggregate data set. Pooled odds ratios (ORs) were estimated for adjusted models that included sex, age, country-r…

MaleOncologyMESH: United KingdomCancer ResearchEpidemiology[SDV]Life Sciences [q-bio]MESH: Neoplasm GradingMESH: SolventsMESH: Occupational ExposureMESH: GliomaTumor gradechemistry.chemical_compound0302 clinical medicineRisk FactorsMESH: New ZealandMESH: Risk FactorsGermanyOdds RatioIsraelYoung adultMESH: AgedOccupationMESH: Middle AgedBrain NeoplasmsAge FactorsMESH: IsraelGliomaMiddle Aged030210 environmental & occupational healthMESH: Case-Control Studies3. Good healthOncologyMESH: Young Adult030220 oncology & carcinogenesisSolventMESH: Brain NeoplasmsFemaleFranceAdultCanadamedicine.medical_specialtyAdolescentCase–control studyJob-exposure matrixMESH: AustraliaYoung Adult03 medical and health sciencesSex FactorsMESH: Sex FactorsMESH: CanadaOccupational ExposureInternal medicineGliomamedicineJournal ArticleHumansMESH: GermanyAgedMESH: AdolescentMESH: Age FactorsMESH: Humansbusiness.industryAustraliaCase-control studyMESH: AdultOdds ratiomedicine.diseaseUnited KingdomConfidence intervalMESH: MaleMESH: Odds RatioMESH: FrancechemistryCase-Control StudiesSolventsNeoplasm GradingSolvent exposurebusinessMESH: FemaleNew Zealand
researchProduct

Assessing the risk of osteonecrosis of the jaw due to bisphosphonate therapy in the secondary prevention of osteoporotic fractures

2012

There is evidence that the use oral bisphosphonates can lead to osteronecrosis of the jaws (ONJ). Although the occurrence of ONJ appears rare among oral bisphosphonates (BPs) users, it is important to know that it exists and can be opportunely minimized. INTRODUCTION: The purpose of this study is to evaluate the association between BPs prescribed for the secondary prevention of osteoporotic fractures and the occurrence of ONJ. METHODS: An Italian record linkage claims database with a target population of around 18 million individuals (6 million over 55 years of age) constituted the data source. We conducted a nested case-control study within a cohort of individuals aged 55+ years old, who w…

Malemedicine.medical_specialtyEndocrinology Diabetes and MetabolismONJDentistryOsteoporosis; fractures; biphosphonatesAdministration OralBisphosphonates Nested case–control study Osteonecrosis of the jaw Osteoporotic fracturesOSTEPOROSISRisk AssessmentAssociationADMINSTRATIVE DATABASESnested case-control studySettore MED/28 - Malattie OdontostomatologicheClaims dataMedicineHumansnested case-control study; osteoporotic fractures; osteonecrosis of the jaw; bisphosphonatesWomenbisphosphonatesAgedSecondary preventionAged 80 and overOral bisphosphonatesBone Density Conservation AgentsDiphosphonatesbusiness.industryMiddle Agedmedicine.diseaseOral BisphosphonateNecrosiosteonecrosis of the jawItalyClaims DataCase-Control StudiesOrthopedic surgeryBisphosphonates; Osteonecrosis of the jaw; Osteoporotic fractures; Nested case-control studyBisphosphonate-Associated Osteonecrosis of the JawFemaleSurgeryProfileBisphosphonate therapyMedical Record LinkagebusinessOsteonecrosis of the jawOsteoporotic Fractures
researchProduct

Phospholipid profiles and hepatocellular carcinoma risk and prognosis in cirrhotic patients.

2018

Background Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide. Phospholipids are now well-recognised players in tumour progression. Their metabolic tissue alterations can be associated with plasmatic modifications. The aim of this study was to evaluate the potential of the plasma phospholipid profile as a risk and prognostic biomarker in HCC. Methods Ninety cirrhotic patients with (cases) or without HCC (controls) were studied after matching for inclusion centre, age, gender, virus infection, cirrhosis duration and Child-Pugh grade. High-performance liquid chromatography coupled with tandem-mass spectrometry was used to quantify the main species of seven categories of …

cirrhosisbiomarkercase–control studyhepatocellular carcinomaphospholipidsResearch PaperOncotarget
researchProduct